Most people take tamoxifen for 5 or 10 years. A few searches of Google Scholar showed just a handful of studies that specifically target Tamoxifen and weight gain. There are studies that suggest there might be a link, and those that fail to find a link. Weight gain is common during breast cancer treatment, but there isn’t enough evidence to prove that it’s a side effect of tamoxifen. Most address the question in the context of more general studies. I had done a bit of research while taking it, I had a year of misery with stiff joints, hot flushes through the roof & feeling sluggish probably because of weight gain. Femara (letrozole): One of the side effects of Femara (letrozole) is weight gain. Letrozole was also shown to have similar efficacy to megestrol acetate in two large randomized studies. It is also used for women who have already had other cancer treatments (eg, tamoxifen). More than 30% of women in the megestrol group had weight gain of ≥5%, and more than 10% had weight gain of ≥10%. A 34-year-old member asked: Can femara (letrozole) cause a miscarriage? Weight increased is found among people who take Letrozole, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years. Weight gain may be more likely in women with breast cancer under the age of 60, who smoke, or who have had a mastectomy. Femara is often given to women who have been taking tamoxifen (Nolvadex, Soltamox) for 5 years.Femara is available in generic form. Talk to your doctor about changing your medication. Selected from data included with permission and copyrighted by First Databank, Inc. Up to 11 percent of people who take Femara experience weight gain. Femara is a non-steroidal aromatase inhibitor (lowers estrogen production) used to treat breast cancer in postmenopausal women. Common side effects of Femara include: hot flashes, ; warmth in your face or chest, This therapy has several side effects, and one of them is weight loss. I'm no longer on Letrozole - long story but nothing to do with my cancer treatment. Weight gain is commonly reported by breast cancer patients on tamoxifen or aromatase inhibitors. What I was finding … Send thanks to the doctor. This portion of the eMedTV archives lists some things you can try if you're on Femara and weight gain occurs (such as limiting your alcohol intake and eating heart-healthy foods). Femara is a potent hormone drug and only your physician can assess if it can be of benefit to you and in what doses. Since weight gain may impact on outcome and compliance we have prospectively assessed the effects of these agents on weight change in three randomised trials for … Aromatase inhibitors aren’t used to reduce recurrence risk in premenopausal women. Dr. Barbara Toppin answered. Specializes in Obstetrics and Gynecology. Dombernowsky et al. Many women gain weight during breast cancer treatment. Femara (chemical name: letrozole) were shown to be more effective at reducing recurrence risk in postmenopausal women and are now used more often than tamoxifen to treat women who’ve gone through menopause. Letrozole is used to treat certain types of breast cancer in women who have already stopped menstruating (postmenopausal). Femara, also known as letrozole, is a drug used for treating breast cancer in postmenopausal women. The phase IV clinical study is created by eHealthMe based on reports of 24,728 people who have side effects when taking Letrozole from the … Female hormones that occur naturally in the body can increase the growth of some breast cancers. Nothing to do letrozole and weight gain my cancer treatment Send thanks to the doctor more studies. Stopped menstruating ( postmenopausal ) a drug used for women who have already had cancer! 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